try a product called kick ick- it really works very well if you follow the directions- get the big bottle- you will need it- try Premium Aquatics, they sell it. Seriously, this stuff really does work, and it works very fast. You have a pretty large bio load, so I hope you have a good skimmer, and a large fuge. Remember follow the directions to the letter. BTW, it really is reef safe. I have used this product, otherwise I wouldnt recomend it.