Nope! In the concentration range I use , there is no detectable effect on pH. Thanks for feedback and support. I've performed this 3 times now. There are no side effects observable. I was paying special attention to my snails and hermit crabs. I've got purple button polyp. So I can't extrapolate the effect of this treatment for other corals. However, this one was doing very well! I've adopted this procedure and now it is the 1st step of my QT treatment: step 1 - 7 days in QT tank with DIY ICK medicine applied every 2 days. step 2 - RO/DI water dips every 24h for 30-60s, depending on stress level. Therapy is complemented by feeding with: garlic extract/vit. C/multivitamin complex soaked food. Application of additional ozonizer can speed up the therapy (the machanism of medications action involves oxidation in water, to create active form of medicine). Moreover, I've performed so called "adsorption assay". After complete 7-day treatment , I've placed 500g of highly active adsorption medium (EHFIAKTIVE, by EHEIM, Germany) in my external filter. Water flow in my additional unit is 650 gph (with filter media) so approx. 8.5x my tank / h. I've been taking water sample every 4h from the treated tank and performing measurements in the lab: 1D proton NMR spectroscopy measurements. According to my measurements the medication is adsorbed to the undetectable level (0.01 ppm) in 16h. So, the conclusion is: it can be effectively removed from the display tank, using standard aquaristic equipment. Enjoy!