hmmm, good read- BUT, I got a case of ICK not to long ago, first thing I did- raise the temp to 88 degress, added melafix and pimafix, shut down the skimmer, then added API aquarium salt to my sump. Waited a few days, helping but not gone- I had already lost two fish- time to get drastic. Searching online I found a product called Kick-Ick, kinda pricey- but not even close to the cost of my beloved fish and my other critters. So I called Premium Aquatic's as they carry this product, and I bought some. After returning my tank to it's normal state, I treated the tank with Kick-Ick- corals and all still in the tank, in two days I didnt see any more ICK on my fish, NONE. So I continued following the direction as per the label- today we are ICK free and my critters are very happy- it has been over a month- no re-occurance- of any ICK or other problems. Kick Ick works really well- at least it did for my 165 gallon reef.