My worst problem was on a 48x24x24 I had way back in OZ I decided it was time to DIY some acrylic HOB Skimmer it lasted the most of a week.
I came home from work to find a huge salt lake in my rented apptment hehe! the carpet was a mess and the tank half empty. My lack of experiance with acrylic was my undoing the ass dropped out and the rests history.

had no tank losses just a moral drop!!!
The stupid thing is that back then I had a huge sump with more spare room in it then you could poke a stick at !!!!
But no internet back then for checking great sites like this one for good info.
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55gl skimmerless, 80lbs live rock,
DIY wavemaker running 3x MJ1200 with hydor deflector.
2 DIY fluidized reactors Carbon & ROWAphos
LIghts- 2x 50/50 atinics T10's , 2x life gro T10's ,
1x20,000K T12, 1x6,000K T10.
Fish-3
Coral-13.